Effects of Exercise Training on Mechanoreflex and Metaboreflex Control in Heart Failure Patients

University of Sao Paulo General Hospital

Status: Completed

Conditions: Heart Failure

Treatments: Other: Aerobic Exercise Training

Study type: Interventional

Funder types: Other

Identifiers

NCT01884142

Ergoreflex

Details and patient eligibility

About

The investigators hypothesize that exercise training would improve the mechanoreflex and metaboreflex control in heart failure patients.

Enrollment: 34 patients

Sex: All

Ages: 30 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with systolic heart failure;
• New York Heart Association (NYHA) class II-III;
• Left ventricular ejection fraction less than 40%;
• Peak Oxygen Consumption less than 20 ml/Kg/min;
• Stable Clinical Status.

Exclusion criteria

• Chronic Obstructive Pulmonary Disease;
• Neuromuscular Diseases;
• Orthopedic Diseases;
• Neurologic Diseases;
• Neoplastic Diseases;
• Recent myocardial infarction or cardiac surgery (less than 6 months);
• Unstable angina pectoris;
• Atrial Fibrillation;
• Pacemakers users;
• Changing medication or hospital admission.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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34 participants in 2 patient groups

Heart Failure Untrained Group

No Intervention group

Description:

Control Group

Heart Failure Exercise-trained Group

Experimental group

Description:

Aerobic Exercise Training

Treatment:

Other: Aerobic Exercise Training