EFFECTS OF EXTRACORPOREAL CYTOKINE ELIMINATION ON HEMODYNAMIA AND MORTALITY IN CRITICAL PATIENTS

Hakan Küçükkepeci

Status: Invitation-only

Conditions: Cytokine Hemadsorption Therapy in Critically Ill Patients Who Have no Microbiological Findings and Develop Vasoplegic Shock

Treatments: Procedure: cytokine hemadsorption therapy

Study type: Observational

Funder types: Other

Identifiers

NCT05984407

652779

Details and patient eligibility

About

Observation of the effects of cytokine adsorbent hemadsorption therapy on hemodynamics and mortality in critically ill patients who developed vasoplegic shock due to hyperinflammation without microbiological findings in the intensive care unit.

Full description

Observation of the effects of cytokine adsorbent hemadsorption therapy on hemodynamics and mortality in critically ill patients who developed vasoplegic shock due to hyperinflammation without microbiological findings and met the inclusion criteria in the Intensive Care Unit between 01.08.2023 and 01.02.2024

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• C-reactive protein (CRP) ≥ 100 mg/l
• Procalcitonin (PCT) < 2 ng/l
• Patients aged 18-80 years who were treated with cytokine adsorption due to vasoplegic shock

Exclusion criteria

• Patients under 18 years of age
• Patients with suspected or proven bacterial cause of vasoplegic shock.
• Those who did not approve to participate in the study
• Patients without vasoplegic shock
• Patients with CRP < 100 mg/l, PCT ≥ 2 μg/L

Trial design

30 participants in 1 patient group

patients with vasoplegic shock

Description:

Application of cytokine hemadsorption therapy in patients with vasoplegic shock without microbiological findings

Treatment:

Procedure: cytokine hemadsorption therapy