Effects of Faba Bean Fractions as Ingredients in Novel Food Products on Glycemia, Appetite and Metabolic Control

U

University of Manitoba

Status

Completed

Conditions

Faba Bean
Insulin
Satiety Hormones
Appetite
Post-prandial Blood Glucose

Treatments

Other: Faba bean starch smoothie
Other: Faba bean protein concentrate smoothie
Other: Non-pulse smoothie smoothie
Other: Faba bean protein isolate smoothie
Other: Faba bean powder smoothie

Study type

Interventional

Funder types

Other

Identifiers

NCT02666586
B2015:110

Details and patient eligibility

About

To describe the effect and mechanisms of action faba bean powder and fractions (protein, starch and fiber) on glucose and insulin homeostasis, food intake, satiety and metabolic regulation in young adults (18 to 30 years).

Full description

The overall objective is to describe the effect and mechanisms of action of faba bean powder and fractions (protein, starch and fiber) on glucose and insulin homeostasis, food intake, satiety and metabolic regulation in young adults (18 to 30 years). The specific objectives are to test the acute effects of different faba bean ingredient smoothie on: 1) post-prandial blood glucose, appetite, satiety hormone and insulin for 200 minutes, and 2) food intake 120 minutes following consumption of the faba bean smoothie. Two short-term acute studies will be conducted to meet these objectives. Both acute studies will follow a randomized, double blinded, balanced, repeated measures design and the same protocol; except one will have an ad libitum pizza meal (study 1), while the other will have a fixed pizza meal (study 2) at 120 minutes. Half the participants will have blood drawn by IV and the other half will be finger prick.

Enrollment

60 patients

Sex

Male

Ages

20 to 30 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • healthy
  • non-smoking males
  • aged 20-30 years (min/max age)
  • a body mass index between 20 and 25 kg/m2 (the range generally accepted as ideal/healthy by Health and Welfare Canada)

Exclusion criteria

  • individuals diagnosed with diabetes
  • those on medication
  • breakfast skippers
  • on an energy restricted diet
  • this study excludes females because appetite and blood glucose during the female menstruation cycle changes due to fluctuations in hormones

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Double Blind

60 participants in 5 patient groups, including a placebo group

Control smoothie
Placebo Comparator group
Description:
Control smoothie with 32 g corn maltodextrin without added faba bean fractions.
Treatment:
Other: Faba bean protein isolate smoothie
Other: Faba bean powder smoothie
Other: Faba bean protein concentrate smoothie
Other: Faba bean starch smoothie
Faba Bean powder smoothie
Experimental group
Description:
Breakfast smoothie with 32 g whole faba bean powder.
Treatment:
Other: Faba bean protein isolate smoothie
Other: Non-pulse smoothie smoothie
Other: Faba bean protein concentrate smoothie
Other: Faba bean starch smoothie
Faba bean protein concentrate smoothie
Experimental group
Description:
Breakfast smoothie with 32 g faba bean protein concentrate.
Treatment:
Other: Faba bean protein isolate smoothie
Other: Faba bean powder smoothie
Other: Non-pulse smoothie smoothie
Other: Faba bean starch smoothie
Faba bean starch smoothie
Experimental group
Description:
Breakfast smoothie with 33 g faba bean starch.
Treatment:
Other: Faba bean protein isolate smoothie
Other: Faba bean powder smoothie
Other: Non-pulse smoothie smoothie
Other: Faba bean protein concentrate smoothie
Faba bean protein isolate smoothie
Experimental group
Description:
Breakfast smoothie with 32 g faba bean protein isolate.
Treatment:
Other: Faba bean powder smoothie
Other: Non-pulse smoothie smoothie
Other: Faba bean protein concentrate smoothie
Other: Faba bean starch smoothie

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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