Effects of Farinelli's Breathing Exercise in COPD Patients

Chulalongkorn University

Status: Completed

Conditions: COPD Patients

Treatments: Other: Diaphragmatic Breathing Exercise; Other: Farinelli's Breathing Exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT04869033

EX PHYSIO SPSC 2

Details and patient eligibility

About

This study was to investigate the effect of Farinelli's breathing exercise on pulmonary function, respiratory muscle strength, aerobic capacity, impact of COPD questionnaires, cytokines, and oxidative stress in patients with Chronic Obstructive Pulmonary Disease (COPD).

Full description

Sixteen patients with COPD (GOLD I) with mild and moderate (GOLD II) severity aged 51 - 80 years old who visited at the outpatient examination room, Phramongkutklao Hospital divided into 2 groups; diaphragmatic breathing group (DB; n=8) and Farinelli's breathing group (FB; n=8). Participants in each group were administered to complete breathing exercise 5 times per week for 8 weeks. Physiological data and pulmonary function (FVC, FEV1, PEF, FEV1/FVC, FEF25-75%, MVV, VC, TV, IRV, ERV and IC), respiratory muscle strength (MIP and MEP), aerobic capacity (6-MWD and VO2max), impact of COPD questionnaire (mMRC and CAT), cytokine (TNF-α and IL-6), and oxidative stress (MDA) were analyzed during Pre- and Post-test.

Enrollment: 16 patients

Sex: All

Ages: 51 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with COPD who treated in Phramongkutklao Hospital
• Have a history of smoking
• FEV1 predicted after bronchodilator more than 50%
• No change in medication in 4 weeks
• No history of acute exacerbation in 4 weeks
• No history of cardiac disease.

Exclusion criteria

• Recurrent of acute exacerbation
• Cannot participate at least 80% of training program (≤ 32 sessions of 40 sessions)
• Unwilling to continue practicing.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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16 participants in 2 patient groups

Farinelli's breathing group

Experimental group

Description:

Complete Farinelli's breathing exercise 5 times per week for 8 weeks.

Treatment:

Other: Farinelli's Breathing Exercise

Diaphragmatic breathing group (control group)

Other group

Description:

Complete Diaphragmatic breathing exercise 5 times per week for 8 weeks.

Treatment:

Other: Diaphragmatic Breathing Exercise