Effects of Fetal, Infant, and Early Childhood Exposures on Adult Cancer Risk in Women

National Institutes of Health Clinical Center (CC)

Status: Completed

Conditions: Breast Cancer; Unspecified Adult Solid Tumor, Protocol Specific

Treatments: Other: questionnaire administration; Procedure: evaluation of cancer risk factors

Study type: Observational

Funder types: NIH

Identifiers

NCT00559039

CDR0000565931

999901015

01-C-N015

Details and patient eligibility

About

RATIONALE: Gathering information about pregnancy, infancy, and early childhood exposures may help doctors identify cancer risk factors, and may help the study of cancer.

PURPOSE: This natural history study is looking at the effects of fetal, infant, and early childhood exposures on adult cancer risk in women.

Full description

OBJECTIVES:

• Determine if fetal, infant, and early childhood exposures are associated with adult cancer risk in women.

OUTLINE: Mothers of nurses complete questionnaires to collect maternal data, such as pregnancy weight gain, diet during pregnancy, maternal pre-eclampsia, gestational diabetes, gestational age at birth, birth weight, and infant feeding practices. Maternal data is linked to other data collected from critical time periods in the nurses's life cycle, such as menarche, first pregnancy, or adult dietary intake.

Enrollment: 128,700 estimated patients

Sex: Female

Ages: 18 to 89 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

DISEASE CHARACTERISTICS:

• Mother of a nurse who is a participant in the Nurses' Health Studies I and II

  • Nurse free of cancer in the year 2000

PATIENT CHARACTERISTICS:

• Not specified

PRIOR CONCURRENT THERAPY:

• Not specified