Effects of Filter Ventilation on Sensory Response, Smoking Topography, and Inhalation in Current Every Day Cigarette Smokers

Roswell Park Comprehensive Cancer Center

Status: Completed

Conditions: Cigarette Smoker; Current Every Day Smoker

Treatments: Behavioral: Tobacco Smoking; Device: Medical Device; Other: Questionnaire Administration

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT04060446

P01CA217806 (U.S. NIH Grant/Contract)

P30CA016056 (U.S. NIH Grant/Contract)

I 68718 (Other Identifier)

NCI-2019-04530 (Registry Identifier)

Details and patient eligibility

About

This trial examines the effects of filter ventilation on sensory response, smoking topography, and inhalation in current every day cigarette smokers. The physical design features of cigarettes directly impact their appeal by influencing cognitive and sensory perceptions. The introduction of a now common design feature, filter ventilation, has led to greater public harm than benefit because of the potential for greater toxicity while enhancing product appeal among smokers. Ventilated cigarettes dilute smoke, which promotes perceptions of ?smoothness? and therefore lower health risk, contributing to the overall appeal of these products. The purpose of this study is to assess whether removing ventilation from cigarette filters lowers cigarette product appeal among smokers.

Full description

PRIMARY OBJECTIVES:

I. To assess the link between marketing proxies for filter ventilation (product descriptors, packaging) and risk beliefs.

OUTLINE:

Patients smoke 5 cigarettes separated by 30 minute washout periods. Between 48 hours and 1 week later, patients smoke another 5 cigarettes separated by 30 minute washout period with CReSSMicro topography measurement device and BioRadio device for recording inhalation patterns.

Enrollment: 8 patients

Sex: All

Ages: 18 to 69 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Currently smoking daily at least 5 cigarettes per day for at least one year
• Primarily using factory-made filtered cigarettes with filter ventilation
• Fair and above physical health
• Fair and above mental health
• Not actively trying to quit smoking or planning to quit in the next 30 days
• Able to converse, read, and write in English
• No alcohol or illegal drug use
• Not pregnant or breastfeeding

Exclusion criteria

• Currently smoking daily less than 5 cigarettes per day for at least one year
• Using roll-your-own cigarettes or unventilated filter cigarettes
• Currently using any other tobacco product daily
• Actively trying to quit smoking or planning to quit in the next 30 days
• Not able to converse, read, and write in English
• Adults unable to consent
• Prisoners
• Poor physical health by self report
• Poor mental health by self report
• Alcohol and illegal drug use
• Pregnant or breastfeeding by self report

Trial design

8 participants in 1 patient group

Observational (smoke cigarettes)

Description:

Patients smoke 5 cigarettes separated by 30 minute washout periods. Between 48 hours and 1 week later, patients smoke another 5 cigarettes separated by 30 minute washout period with CReSSMicro topography measurement device and BioRadio device for recording inhalation patterns.

Treatment:

Other: Questionnaire Administration

Device: Medical Device

Behavioral: Tobacco Smoking