Effects of Gastrostomy on Amyotrophic Lateral Sclerosis

University Hospital, Clermont-Ferrand

Status: Completed

Conditions: Amyotrophic Lateral Sclerosis

Study type: Observational

Funder types: Other

Identifiers

NCT00337402

CHU63-0001

Details and patient eligibility

About

Results about effects of symptomatic treatment on QoL appears conflicting in ALS patients. Moreover no clear effects of gastrotomy have be shown on survival. Prospective study on effect of tube feeding, QoL and survival is performed in 17 teaching hospitals in France (observational study)

Full description

Following data have been recorded each three months: QoL (MOS-SF 36 and ALSAQ), bodily mass index, testing and ALS-FRS scale, functional respiratory measures, impedance analysis, and the time for tube feeding procedure, the conditions of the acceptance and side-effects of gastrotomy

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients > 18 years-old
• ALS certain or probable
• vital capacity (respiratory) > 70 %
• under riluzole

Exclusion criteria

• ALS in family
• other conditions affected survival and QoL
• cognitive impairment