Effects of Gum Arabic Ingestion on Hormonal and Metabolic Changes in Patients With Polycystic Ovary Syndrome (GA&PCO)

Lamis Kaddam

Status: Unknown

Conditions: Polycystic Ovary Syndrome

Treatments: Dietary Supplement: Acacia Senegal extract; Dietary Supplement: Pectin

Study type: Interventional

Funder types: Other

Identifiers

NCT04215380

GA& PCO

Details and patient eligibility

About

To assess the effects on hormonal and metabolic changes in the PCOs patients after ingestion of Arabic gum

Full description

Polycystic ovary syndrome (PCOS) affects 5-20% of women of reproductive age worldwide it increases the risk for type 2 diabetes mellitus, cerebrovascular and cardiovascular events and not to mention it is one of the main causes of infertility. in the management of PCOS life style modification like weight reduction is necessary and recently it was discovered that GA ingestion causes significant reduction in BMI and body fat percentage among healthy adult females.so if GA could also affect the hormones and the metabolic changes in PCOs is going to be useful in decreasing the comorbidities and even treating PCOs.

Enrollment: 60 estimated patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who are diagnosed with PCO by independent Gynecologist

Exclusion criteria

• Diabetic patients
• Menopausal women
• History of allergy to Gum Arabic

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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60 participants in 2 patient groups, including a placebo group

Intervention Group

Experimental group

Description:

This arm will receive 100% natural Gum Arabic provided in a powder form as 30-grams-dose for 12 weeks

Treatment:

Dietary Supplement: Acacia Senegal extract

Control group

Placebo Comparator group

Description:

This group will be provided with pectin powder provided as two-gram-dose fo

Treatment:

Dietary Supplement: Pectin