Effects of Gum Chewing on Recovery of Bowel Function Following Abdominal Surgery for Endometrial and Ovarian Cancer

Chiang Mai University

Status and phase: Withdrawn; Phase 3; Phase 2

Conditions: Paralytic Ileus

Treatments: Behavioral: Gum chewing

Study type: Interventional

Funder types: Other

Identifiers

NCT01389986

GUM-ET/OV

Details and patient eligibility

About

Following extensive abdominal surgery for the treatment of endometrial or ovarian cancer, paralytic ileus frequently develops. Gum chewing can promotes the return of bowel function through the cephalic-vagal reflex and increased intestinal enzymes secretion.

The objectives of this study are to evaluate effects of adding gum chewing to the conventional postoperative feeding protocol on the return of bowel function, its related complications, and patients' satisfaction.

Sex: Female

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing staging or cytoreductive surgery for primary endometrial or ovarian cancer at Maharaj Nakorn Chiang Mai hospital

Exclusion criteria

• Perioperative hyperalimentation
• Recent chemotherapy (within 3 weeks before surgery)
• Previous bowel surgery
• Inflammatory bowel diseases
• Previous abdominal or pelvic radiation
• Need for immediate postoperative endotracheal intubation
• Need for postoperative admission to intensive care unit
• Undergoing emergency surgery with oral intake of fluid or food within 4 hours before surgery

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

0 participants in 2 patient groups

Gum chewing

Experimental group

Description:

Gum chewing (30 minutes in duration each time, 4 times/days at the usual time of meal, until the first flatus) in addition to conventional postoperative feeding schedule

Treatment:

Behavioral: Gum chewing

Conventional

No Intervention group

Description:

Conventional postoperative feeding schedule