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Effects of Gut Peptides on Bone Remodeling (KS-3)

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University of Copenhagen

Status

Completed

Conditions

Healthy

Treatments

Other: GLP-2+GIP
Other: Placebo
Other: Glucose-dependent insulinotropic polypeptide (GIP)
Other: Glucagon-Like Peptide-2 (GLP-2)

Study type

Interventional

Funder types

Other

Identifiers

NCT03574064
UCPH-KS-3-18

Details and patient eligibility

About

We will investigate effects of gut hormones on bone remodeling.

Enrollment

10 patients

Sex

Female

Ages

50 to 80 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Women Age above 50 years Postmenopausal Caucasian BMI 18.5 to 28.0 kg/m2.

Exclusion criteria

Smoking Medication believed to influence study outcome Weight change more than 3 kg whitin the last 3 months Overweight surgery Intestinal surgery Hgb<7,0 mmol/L Decreased renal function

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Double Blind

10 participants in 4 patient groups, including a placebo group

GLP-2
Experimental group
Description:
Glucagon-Like Peptide-2 (GLP-2)
Treatment:
Other: Glucagon-Like Peptide-2 (GLP-2)
GIP
Experimental group
Description:
Glucose-dependent Insulinotropic polypeptide (GIP)
Treatment:
Other: Glucose-dependent insulinotropic polypeptide (GIP)
GLP-2+GIP
Experimental group
Description:
GLP-2+GIP
Treatment:
Other: GLP-2+GIP
Placebo
Placebo Comparator group
Description:
Placebo
Treatment:
Other: Placebo

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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