Effects of Heating Transfusion on Brain Function

General Hospital of Ningxia Medical University

Status: Completed

Conditions: Blood Transfusion

Study type: Observational

Funder types: Other

Identifiers

NCT01930305

NXKJGG2012

Details and patient eligibility

About

To inversitage whether routine warming of blood is harmful to brain fuction of sugical patients receiving massive transfusion.

Full description

Hypothermia is an effective therapeutic intervention to reduce hypoxic ischemia brain injury in animal experiments and in clinics.In a recent study, it has been shown that perioperative warming was associated with a higher incidence of cognitive dysfunction in elderly patients.Therefore, we hypothesised that perioperative heating transfusion have a side effect on brain function of surgical patients.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• adult patients scheduled for major surgery under general anesthesia and they probably need a blood transfusion during the procedure.

Exclusion Criteria:•Patients with a history of stroke, central nervous system disease , metabolic disturbance, psychiatric illness, hearing impairment, drug abuse or unwilling to participate in assessment