Effects of Herbal Products on Reduction of Radiation-induced Dermatitis in Breast Cancer Patients

Chulabhorn Cancer Center

Status: Completed

Conditions: Adverse Effect of Radiation Therapy; Radiodermatitis; Breast Neoplasms

Treatments: Other: Control; Other: Thunbergia cream; Other: Centella cream; Other: Cucumber cream

Study type: Interventional

Funder types: Other

Identifiers

NCT02922244

005/2559

Details and patient eligibility

About

The herbal products on reduction of radiation-induced dermatitis in patients with breast cancer

Full description

To compare the effect of each herb extracts to protect the skin from the adverse effects of radiation therapy in patients with breast cancer with herbal extract products.

Enrollment: 150 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Aged 20 years old or older,
• Diagnosed with Breast cancer
• On course of external Radiation therapy

Exclusion criteria

• Pregnant
• Previously underwent external Radiation therapy
• Illiterate

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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150 participants in 5 patient groups, including a placebo group

Standard skin care

No Intervention group

Description:

standard skin care

Control

Placebo Comparator group

Description:

Moisture Cream

Treatment:

Other: Control

Cucumber cream

Active Comparator group

Description:

Apply Cucumber cream everyday after radiation therapy on the treatment aria skin.

Treatment:

Other: Cucumber cream

Centella cream

Active Comparator group

Description:

Apply Centella asiatica cream everyday after radiation therapy on the treatment aria skin.

Treatment:

Other: Centella cream

Thunbergia cream

Active Comparator group

Description:

Apply Thunbergia cream everyday after radiation therapy on the treatment aria skin.

Treatment:

Other: Thunbergia cream