Effects of High Protein Diet on Muscle Mass, Strength, and Physical Performance in Postmenopausal Women

Hospital de Clinicas de Porto Alegre

Status: Completed

Conditions: Physical Disability; Muscle Loss

Treatments: Other: Control Diet; Other: High Protein Diet

Study type: Interventional

Funder types: Other

Identifiers

NCT03652584

170019

Details and patient eligibility

About

Despite the importance of preventing muscle mass loss during senescence, only a few studies have investigated the relationship between diet and muscle mass in postmenopausal women. Therefore, the aim of this study is to investigate whether controlled protein consumption at the current Recommended Daily Allowance (RDA = 0.8 g/kg body weight) or twice the RDA (1.6 g/kg body weight) affects skeletal muscle mass, strength, and physical performance in postmenopausal women. In this parallel-group trial, participants were randomized for 6 months to low glycemic index diets with controlled protein consumption at the current RDA or twice the RDA, aimed to balance energy needs.

Enrollment: 28 patients

Sex: Female

Ages: 65+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Postmenopausal women
• Without mobility aids, able to perform activities of daily living independently

Exclusion criteria

• Use of hormone therapy in the past 3 months
• Insulin therapy
• Previous diagnosis of heart disease
• Untreated thyroid diseases
• Conditions affecting neuromuscular function

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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28 participants in 2 patient groups

High Protein Diet

Experimental group

Description:

Low glycemic index dietary plan with 1.6 g/kg/day of protein for 6 months

Treatment:

Other: High Protein Diet

Control Diet

Active Comparator group

Description:

Low glycemic index dietary plan with 0.8 g/kg/day of protein for 6 months

Treatment:

Other: Control Diet