Effects of HIIT on Metabolic Syndrome

Coventry University

Status: Unknown

Conditions: Dyslipidemias; Obesity; Blood Pressure; Metabolic Syndrome; Sedentary Behavior

Treatments: Behavioral: Low Volume-High Intensity Interval Training; Behavioral: Moderate Intensity Continuous Training

Study type: Interventional

Funder types: Other

Identifiers

NCT04133129

P72554

Details and patient eligibility

About

The project aims to find out the differences between two different types of structured training interventions have on the lipid profile of persons with diagnosed dyslipidemia. Each training intervention will last for 12 weeks. Subjects participating in the project will undergo a series of tests before and after the training intervention which will allow us to make conclusions.

Full description

The purpose of this project is to compare the effect that two different types of aerobic training modes have on the lipid profile of subjects with pre-symptoms of metabolic syndrome. One training mode will involve High-Intensity Interval Training and the other will involve medium intensity continuous training. The desired outcomes of this project are to know the effects of both modes of training have on the long-term on the lipid profile in order to help develop a nonpharmacologic alternative to prevent or treat metabolic syndrome and to know how affective and enjoyment responses are affected by the different modes of training. The Project lasts for 16 weeks. Training will take place during weeks 3 and 14 of the project. The project will be described fully to the participants during the 1st week. In addition to this, their rights as participants will be explained in addition to any possible ethical issues that might require clarifying. Once the subjects have agreed to take part in the research they will undergo a series of tests in order to asses their cardiorespiratory fitness and their lipids profile. Before starting the training intervention participants will be randomly assigned to one of the 3 different groups; Control, Medium Intensity Continuous Training and Low Volume High-Intensity Interval Training. Between weeks 3 and 14 subjects will take part in 3 training sessions per week. At week 15 and 16 subjects will undergo the same tests as during week 1 and 2.

Enrollment: 180 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Fasted Blood Glucose >100 mg/dL
• Total Cholesterol >200 mg/dL
• Blood Pressure >130/90 mmHg
• Do not partake in more than 150 min/week of moderate to vigorous exercise

Exclusion criteria

• Existing or past medical history of vascular disease, cancer, diabetes, osteoporosis, neurological, kidney, pulmonary, digestive (Coeliac disease), thyroidal disease.
• Musculoskeletal injuries
• Neuromuscular disorders or injuries
• Individuals with a pacemaker

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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180 participants in 3 patient groups

LV-High Intensity Interval Training

Experimental group

Description:

2 x 4 minutes at 85%-95% of Heart rate max.

Treatment:

Behavioral: Low Volume-High Intensity Interval Training

Moderate Intensity Continuous Training

Experimental group

Description:

1 x 45 minutes at 65%-75% of Heart rate max.

Treatment:

Behavioral: Moderate Intensity Continuous Training

Control Group

No Intervention group

Description:

They will not be prescribed any training and will be asked to continue with their normal lifestyle.