Effects of Home-based vs. Clinic-based Rehabilitation on Sensorimotor, Cognition, Daily Function, and Participation

Chang Gung Medical Foundation

Status: Completed

Conditions: Chronic Stroke

Treatments: Behavioral: bilateral training with and without mirror feedback

Study type: Interventional

Funder types: Other

Identifiers

NCT02364232

103-3962A3

Details and patient eligibility

About

The purpose of this study was to compare the treatment effects of home-based or clinic-based bilateral training with and without mirror feedback programon on physiological markers, sensorimotor, cognition, daily functions, and participation among patients with chronic stroke.

Enrollment: 24 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• The most recent stroke was between 1 month and 5 years
• No serious cognitive impairment (MMSE≥21)
• FMA score =18-62
• No serious muscle spasticity in shoulder, elbow, wrist and finger (MAS≤3)
• Modified rankin Scale=2 to 4

Exclusion criteria

• Aphasia that might interfere with understanding instructions
• Stroke in areas other than the brain and brainstem, such as the cerebellum
• other neurological disease, such as dementia
• Muscle and joint have serious pain and inflammatory swelling in affected side.
• Cannot control hypertension, heart disease and serious throbosis

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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24 participants in 2 patient groups

Home-based

Experimental group

Description:

Participants in home-based training graoup will receive 1.5 hours/ day, 3 days a week, for 4 contious weeks at home. Participants will receive 2 training stages, including bilateral training with mirror feedback for 30-45 minutes and functional training for 45-60 minutes. Each training stage hase to include above 2 activities.After the end of the home-based training, a four-week wash-out period followed. Then, patients will receive the clinic-based training for 4 continuous weeks. Before and after the treatment, a total of 4 evaluations were conducted, including clinical assessments and blood test (each 9c.c.). One month after the end of the course of treatment will be assessed.

Treatment:

Behavioral: bilateral training with and without mirror feedback

Clinic-based

Active Comparator group

Description:

Participants in clinic-based training graoup will receive 1.5 hours/ day, 3 days a week, for 4 contious weeks at home. Participants will receive 2 training stages, including bilateral training with mirror feedback for 30-45 minutes and functional training for 45-60 minutes. Each training stage hase to include above 2 activities.After the end of the clinic-based training, a four-week wash-out period followed. Then, patients will receive the home-based training for 4 continuous weeks. Before and after the treatment, a total of 4 evaluations were conducted, including clinical assessments and blood test (each 9c.c.). One month after the end of the course of treatment will be assessed.

Treatment:

Behavioral: bilateral training with and without mirror feedback