Effects of Hypothermia on Delayed Neurocognitive Recovery (DNR): an Observational Trial Among Patients Undergoing Cardiac-Surgery

University of Padova

Status: Completed

Conditions: Emergence Delirium; Cognitive Dysfunction; Hypothermia

Treatments: Procedure: Hypothermia during Extracorporeal Circulation

Study type: Observational

Funder types: Other

Identifiers

NCT03636074

Zivago

Details and patient eligibility

About

Post-operative cognitive dysfunction is a common disease in patient undergoing general anaesthesia, especially in older patients. No correlations have been yet studied between intraoperative hypothermia and incidence of Delayed Neurocognitive Recovery. Investigators are going to estimate the Relative Risk of Hypothermia and emergence of Post-operative cognitive dysfunction in cardiac-surgery patients.

Enrollment: 168 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adults patients undergoing Cardiac - Surgery intervention with extracorporeal circulation

Exclusion criteria

• Neurological disease before surgery
• Sedation in Cardiac-Surgery Intensive Unit > 6 hours
• Cerebral regional Oxygen saturation <20% baseline during surgery

Trial design

168 participants in 2 patient groups

Hearth-valve surgery

Treatment:

Procedure: Hypothermia during Extracorporeal Circulation

Hearth bypass surgery

Treatment:

Procedure: Hypothermia during Extracorporeal Circulation