Effects of Implementing a High Potassium Diet in Heart Failure Patients

Samuel Lunenfeld Research Institute, Mount Sinai Hospital

Status: Completed

Conditions: Heart Failure

Treatments: Other: High potassium diet

Study type: Interventional

Funder types: Other

Identifiers

NCT03059680

MSH 11-0259-A

Details and patient eligibility

About

This study evaluates the safety and physiologic effects of increasing dietary potassium intake in individuals with heart failure.

Enrollment: 30 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients classified as having HF, both systolic and diastolic.
• New York Heart Association class II-III symptoms.
• Treatment with an beta blocker, ACE inhibitor, or angiotensin receptor blocker without any adjustment over the previous month
• Intake at baseline of ≤ 3 servings of fruits and vegetables per day. Servings defined by Health Canada's food guide.

Exclusion criteria

• Patients with an episode of decompensated heart failure, acute coronary syndrome, or revascularization within the previous 3 months of study inclusion.
• Patients receiving insulin therapy
• Glomerular filtration rate < 40mL/min/1.73 m2
• Pregnancy and lactation (women of childbearing potential will be included but will have to have a negative pregnancy test prior to inclusion).
• Inability to provide informed consent.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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30 participants in 2 patient groups

High potassium diet group

Experimental group

Description:

Individuals in this arm were asked to increase dietary potassium intake over a 4 week period. This was achieved through an increase in consumption of fruits and vegetables.

Treatment:

Other: High potassium diet

Usual diet group

No Intervention group

Description:

Individuals in this group were asked to continue habitual dietary intake