Effects of Increased Muscle Mass on Resting Metabolic Rate

University Hospital, Linkoeping

Status: Completed

Conditions: Healthy Subjects

Treatments: Procedure: Isometric exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT01325038

Beach08

Details and patient eligibility

About

Healthy males are randomized to isometric exercise for three months with either extra protein or extra calories in the form of a fast food meal/day in order to study if increase in muscle mass increases resting metabolic rate and if this is affected by presumed increased caloric intake as compared with only proteins.

Body-composition was measured with Dual-Energy X-ray Absorbimetry (DEXA) and RMR was measured by registration of CO2 production and O2 consumption.

Enrollment: 24 patients

Sex: Male

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy males

Exclusion criteria

• significant disease
• inability to exercise

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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24 participants in 2 patient groups

extra protein supplement

Active Comparator group

Description:

isometric training with addition of extra protein

Treatment:

Procedure: Isometric exercise

extra food supplement

Active Comparator group

Description:

isometric exercise with addition of extra food and calories: one fast food meal/day

Treatment:

Procedure: Isometric exercise