Effects of Inferior Mesenteric Artery Preservation in Laparoscopic Colorectal Resection for Diverticular Disease. (EIMAP)

University of Roma La Sapienza

Status: Completed

Conditions: Colonic Diverticuar Disease; Defecatory Functions; Fecal Incontinence; Constipation

Treatments: Procedure: IMA sectioning; Procedure: IMA preserving

Study type: Interventional

Funder types: Other

Identifiers

NCT06506552

DS-056

Details and patient eligibility

About

This is a prospective randomized study aimed to verifying the short and long-term results of inferior mesenteric artery preservation following colorectal resection for diverticular disease

Full description

This study wants to demonstrate that the preservation of the inferior mesenteric artery allow to improve postoperative defecatory function and improve patient's quality of life.

Enrollment: 300 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• BMI < 35
• ASA I-III
• Hinchey I-III

Exclusion criteria

• BMI > 35
• ASA IV
• Hinchey IV
• Previous procedures that could have been modified the nervous mesenteric pattern (surgery, radiotherapy or chemotherapy)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

300 participants in 2 patient groups

Inferior mesenteric artery preservation

Experimental group

Description:

Performing colorectal resection for diverticular disease the IMA was preserved ligating the sigmoids arteries close to colonic wall.

Treatment:

Procedure: IMA preserving

Inferior mesenteric ligation

Active Comparator group

Description:

Performing colorectal resection the IMA was sectioned just below the origin of left colic artery.

Treatment:

Procedure: IMA sectioning