Effects of Inspiratory and Expiratory Pressure Training Methods in Patients With Chronic Obstructive Pulmonary Disease

Zhujiang Hospital

Status: Unknown

Conditions: Chronic Obstructive Pulmonary Disease(COPD)

Treatments: Device: mixed training group; Device: inspiratory pressure training group

Study type: Interventional

Funder types: Other

Identifiers

NCT02326181

ZJH21400964

Details and patient eligibility

About

The study will investigate the effects of different training types ,including combined inspiratory with expiratory pressure threshold training,inspiratory pressure threshold training on patients with chronic obstructive airway disease and investigate whether expiratory pressure threshold training associated with inspiratory pressure threshold training would be better than inspiratory pressure threshold training alone, with regard to exercise capacity, respiratory muscle strength and endurance.

Full description

We will study 60 patients diagnosed of chronic obstructive pulmonary disease.The monitoring will be done for 8 weeks. Pressure-threshold respiratory trainers were calibrated to provide different loads according to the patients against inspiration (IMST) or expiration (EMST). Those chronic obstructive pulmonary disease clinically stable patients stratified from mild to very severe GOLD stages, were blinded to randomly divided into 3 different groups: a)control group:without any training;b) inspiratory and expiratory pressure threshold training group: trained with the pressure threshold trainer twice time daily with 15minutes' duration;c)inspiratory pressure threshold training group:trained with the pressure threshold trainer twice time daily with 15 minutes' duration,different from the b group,the expiratory pressure threshold is calibrated at 0.

Enrollment: 80 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Clinically stable COPD with diagnosis of forced expiratory volume at one second(FEV1)/forced vital capacity(FVC) < 70%

Exclusion criteria

Cancer Unstable heart disease Neuromusculoskeletal disorder mental disorder Active smokers

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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80 participants in 3 patient groups

control group

No Intervention group

Description:

without inspiratory and expiratory pressure threshold training

inspiratory pressure training group

Experimental group

Description:

The patients will perform daily in 2 sessions of 30 minutes, using a pressure threshold trainer.

Treatment:

Device: inspiratory pressure training group

mixed training group

Experimental group

Description:

The patients will perform daily in 2 sessions of 30 minutes, using a pressure threshold trainer.

Treatment:

Device: mixed training group