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Effects of Inspiratory Muscle Training in Addition to Pulmonary Rehabilitation in Patients With COPD Exacerbation

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National Taiwan University

Status

Completed

Conditions

Exacerbation Copd

Treatments

Other: pulmonary rehabilitation
Other: inspiratory muscle training

Study type

Interventional

Funder types

Other

Identifiers

NCT04802096
202012102RINC

Details and patient eligibility

About

Inspiratory muscle weakness, limited functional exercise capacity and worse quality of life have been shown in patients with exacerbation of chronic obstructive pulmonary disease (COPD). Recommendations from clinical practice guideline state that promoting pulmonary rehabilitation after exacerbation can improve the conditions above. Inspiratory muscle training (IMT) has been proven to enhance inspiratory muscle strength and endurance in patient with stable COPD. However, there is less research on whether IMT in addition to pulmonary rehabilitation after exacerbation can benefit inspiratory muscle function, functional exercise capacity and quality of life in patients with COPD. The purpose of this study is to examine the effects of IMT in addition to pulmonary rehabilitation on respiratory muscle function, functional exercise capacity and quality of life in patients with exacerbation of chronic obstructive pulmonary disease.

Enrollment

16 patients

Sex

All

Ages

20+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • age > 20 years old
  • diagnosed as exacerbation of COPD
  • maximal inspiratory pressure (MIP) < 80 cmH2O

Exclusion criteria

  • any clinical diagnosis that will influence the measurement, including any history of neuromyopathy
  • angina, acute myocardial infarction in the previous one month
  • pregnancy
  • participated in inspiratory muscle training program in the previous three months
  • any psychiatric or cognitive disorders, for example: Mini-Mental State Examination (MMSE) < 24, that will disturb the communication and cooperation of the study

Trial design

Primary purpose

Supportive Care

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

16 participants in 2 patient groups

Inspiratory muscle training combined pulmonary rehabilitation
Experimental group
Treatment:
Other: pulmonary rehabilitation
Other: inspiratory muscle training
Sham inspiratory muscle training combined pulmonary rehabilitation
Sham Comparator group
Treatment:
Other: pulmonary rehabilitation

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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