Effects of Inspiratory Muscle Training in Chronic Obstructive Pulmonary Disease (COPD) (IMTCO)

Schön Klinik Berchtesgadener Land

Status: Completed

Conditions: Inspiratory Muscle Weakness; COPD

Treatments: Other: Inspiratory Muscle Training

Study type: Interventional

Funder types: Other

Identifiers

NCT01903772

IMTCO

Schön Klinik BGL (Other Identifier)

Details and patient eligibility

About

The additional effect of inspiratory muscle training as an adjunct to a general exercise training program in patients with COPD with inspiratory muscle weakness will be studied. The main hypothesis is that inspiratory muscle training combined with an exercise training program improves functional exercise capacity more than an exercise training program without the addition of an inspiratory muscle training program.

Enrollment: 72 patients

Sex: All

Ages: 40 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with COPD
• Eligible to participate in an inpatient pulmonary rehabilitation program of 3 weeks
• Pi,max <60 centimeters of water or <50% of the predicted normal value

Exclusion criteria

• Major comorbidities preventing successful participation in an 8 week exercise training intervention
• use of non-invasive ventilation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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72 participants in 2 patient groups

Inspiratory Muscle Training

Experimental group

Description:

Procedure: Inspiratory Muscle Training Three times daily inspiratory muscle training (2x30 breaths) at an intensity of \>50% Pi,max

Treatment:

Other: Inspiratory Muscle Training

Sham Inspiratory Muscle Training

Sham Comparator group

Description:

Twice daily inspiratory muscle training (3x30 breaths) at an intensity of 5 centimeters of water (H2O)

Treatment:

Other: Inspiratory Muscle Training