Effects of Inspiratory Muscle Training in COPD (IMTCO)

Catholic University (KU) of Leuven

Status and phase: Completed; Phase 3

Conditions: Inspiratory Muscle Weakness; COPD

Treatments: Procedure: Inspiratory Muscle Training

Study type: Interventional

Funder types: Other

Identifiers

NCT01397396

S52852

Details and patient eligibility

About

The additional effect of inspiratory muscle training as an adjunct to a general exercise training program in patients with COPD with inspiratory muscle weakness will be studied. The main hypothesis is that inspiratory muscle training combined with an exercise training program improves functional exercise capacity more than an exercise training program without the addition of an inspiratory muscle training program.

Enrollment: 208 patients

Sex: All

Ages: 40 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with COPD
• Eligible to participate in a exercise training intervention of 8 weeks
• Pi,max <60cmH2O or <50% of the predicted normal value

Exclusion criteria

• Major comorbidities preventing successful participation in an 8 week exercise training intervention

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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208 participants in 2 patient groups, including a placebo group

Inspiratory Muscle Training

Experimental group

Description:

Inspiratory Muscle Training

Treatment:

Procedure: Inspiratory Muscle Training

Sham IMT

Placebo Comparator group

Description:

Sham Inspiratory Muscle Training

Treatment:

Procedure: Inspiratory Muscle Training