Effects of Inspiratory Muscle Training in Patients With Pulmonary Hypertension

Dokuz Eylül University (DEU)

Status: Completed

Conditions: Hypertension, Pulmonary

Treatments: Other: Inspiratory muscle training

Study type: Interventional

Funder types: Other

Identifiers

NCT04152187

2018.KB.SAG.099 (Other Grant/Funding Number)

Pulmonary Hypertension

Details and patient eligibility

About

This study aims to determine the possible effects of inspiratory muscle training on cardiovascular, respiratory, physical and psychosocial functions in patients with PH.

Full description

Pulmonary Hypertension (PH) is a hemodynamic finding related to increase in pulmonary artery pressure. Because PH disease is a progressive, rare disease, it is important for this disease group to prolong the life span and to increase the quality of life and functional capacity. PH patients have been shown to have weakness in peripheral and respiratory muscles.

Patients will be randomly assigned to the inspiratory muscle training and control group. Inspiratory muscle training will be initiated in accordance with the patient at a range of 40-60%. İnspiratory muscle training will be given based on the assessments by the physiotherapist. Patients with PH who come to the routine outpatient clinic and volunteer will be included in the study. The first session will be the evaluation session and the 8-week inspiratory muscle training will be given, the other group will be the control group only. Dyspnoea, diaphragm thickness, pulmonary function, respiratory and peripheral muscle strength, blood pressure, arterial stiffness, physical activity, anxiety, depression and quality of life assessments will be repeated before and after the treatment.

Enrollment: 24 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of Pulmonary Hypertension
• According to the New York Heart Association functional class II - III
• Cases receiving stable medication for 3 months

Exclusion criteria

• Conditions which can limit the assessments
• Severe ischemic heart disease
• Acute cor pulmonale

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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24 participants in 2 patient groups

Inspiratory muscle training (IMT)

Experimental group

Description:

Patients will receive IMT for 30 min (15x2), 7 times per week for 8 weeks using inspiratory muscle trainer device (PowerBreathe). During training, patients will be instructed to maintain diaphragmatic breathing. Inspiratory load will be set at 40-60% of maximum inspiratory pressure. Each week, six training sessions will be held at home and a training session will be supervised with physiotherapist.

Treatment:

Other: Inspiratory muscle training

Control

No Intervention group

Description:

No additional intervention