Effects of Intraoperative Oxygen Therapy on Oxygenation of Newborns Born Via Elective Cesarian Section

University of Szeged (SZTE)

Status: Completed

Conditions: Obstetrical Complication of Anesthesia

Treatments: Other: Oxygen

Study type: Interventional

Funder types: Other

Identifiers

NCT02804555

Maternal hyperoxia

Details and patient eligibility

About

In this study the investigators examine the effects of intraoperative oxygen administration to the mother on certain enzyme functions of the newborn. With this object blood samples are taken from the newborn's umbilical chord - which is otherwise a routine practice at the investigators clinic - and the mother's radial artery in parallel with umbilical clamping and cutting for blood gas and reactive oxygen species analyses. Samples are analyzed locally in a properly equipped laboratory.

Full description

Whole-blood superoxide and hydrogen peroxide production was measured from the newborn's umbilical chord.

Enrollment: 107 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Elective cesarean section.
• Signed informed consent form.

Exclusion criteria

• Subject meets the definition of a vulnerable subject as defined in International Organization for Standardization 14155:2011.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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107 participants in 2 patient groups

Oxygen support

Active Comparator group

Description:

5 liter / minute oxygen has given to the mothers on face mask.

Treatment:

Other: Oxygen

Room air

No Intervention group

Description:

Oxygen support has not given to the mothers.