Effects of Intrathecal Local Anesthetics on Left Ventricular Global Longitudinal Strain

Penn State Health

Status: Completed

Conditions: Spinal Anesthetics Causing Adverse Effects in Therapeutic Use; Global Cardiac Wall Motion Dysfunction; Left Ventricular Dysfunction

Treatments: Drug: Intrathecal local anesthesia

Study type: Observational

Funder types: Other

Identifiers

NCT05650008

21263

Details and patient eligibility

About

The objective of this study is to assess the effects of intrathecal local anesthetics on left ventricular global longitudinal strain (LVGLS) using transthoracic echocardiography (TTE).

Enrollment: 10 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adult patients undergoing elective knee and hip replacements under spinal anesthesia

Exclusion criteria

• Patients who do not wish to consent
• Patients with contraindications to TTE
• Patients with reduced left ventricular systolic function as defined by LV ejection fraction < 50% on pre-operative echocardiography
• Patients with body mass index greater than 40
• Non-English-speaking subjects
• Cognitively impaired adults