Effects of Intrathecal Midazolam (1mg) With Hyperbaric Bupivacaine 0.5% (15mg) for Spinal Anesthesia for C-section

Superior University

Status: Active, not recruiting

Conditions: Cesarean Section Complications

Treatments: Diagnostic Test: group 1

Study type: Observational

Funder types: Other

Identifiers

NCT06748794

MSAHS/Batch-Spring23/049

Details and patient eligibility

About

This study evaluates the effects of intrathecal midazolam (1 mg) combined with hyperbaric bupivacaine 0.5% (15 mg) for spinal anesthesia in cesarean section patients.

Full description

The addition of midazolam, a benzodiazepine with analgesic and anxiolytic properties to bupivacaine is hypothesized to enhance the quality of anesthesia and postoperative pain relief without significant side effects. A comparative analysis was conducted to assess sensory and motor block characteristics, postoperative analgesia duration, maternal hemodynamic stability, and neonatal outcomes.

Enrollment: 64 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Female patients presented for elective cesarean section.
• All ASA I & II patients .
• Age between 18 to 35 years.

Exclusion criteria

• Contraindication to spinal anesthesia.
• Patient not willing or previous bad experience with it.
• All ASA III & IV class was excluded from the study.
• Patients with documented bleeding disorders i.e. low platelet count, deranged PT/APTT/INR, DIC etc.
• Hypertensive patients
• Patients with Diabetes mellitus.
• Obese patients BMI >30.
• PIH (pre- eclampsia and eclapmsia)"