Effects of Inulin on Satiety and Food Intake

Maastricht University Medical Centre (MUMC)

Status: Completed

Conditions: Obesity

Treatments: Dietary Supplement: placebo; Dietary Supplement: inulin

Study type: Interventional

Funder types: Other

Identifiers

NCT01025375

HumBio_Westerterp08_2

Details and patient eligibility

About

To assess the effect of inulin on appetite profile ratings, food intake and satiety hormones.

Full description

Based upon a slower digestion and the fermentation in the intestinal tract, food containing soluble dietary fibres, such as inulin, is hypothesized to be more satiating, and to limit energy intake, in humans. Does supplementation of inulin (at 2 dosages) versus placebo over 13 consecutive days in normal to overweight men and women, lead to an increase in satiety, a reduction in food intake and stronger postprandial increases in GLP-1 and PYY?

Enrollment: 30 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age between 18 and 60 years
• BMI between 23 and 28 kg/m2
• dietary unrestraint (TFEQ: F1<9)

Exclusion criteria

• age under 18 and above 60 years
• BMI under 23 and above 28 kg/m2
• dietary restraint (TFEQ: F1>9)
• use of medication
• pregnant or breastfeeding