Effects of IPV Assessed With Functional Imaging

Antwerp University Hospital (UZA)

Status: Unknown

Conditions: Chronic Obstructive Pulmonary Disease

Treatments: Device: intrapulmonary percussive ventilation; Other: standard treatment

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT01671540

PML_Kine_IPV

artesis_G018 (Other Identifier)

Details and patient eligibility

About

In this study the invetigators seek an answer on the following hypothesis:

• What are the long term effects of an IPV treatment evaluated with classical outcome parameters? (FEV1, Raw)
• Is the possible effect noticeable on the novel technique and is this comparable with the classical outcome parameters?

Full description

A Multicenter study conducted in university Hospital Antwerp (UZA) and ZNA Middelheim.

Tests are taken before and after one week IPV treatment. IPV is applied for 1 week during the physical therapy treatment of chronic obstructive pulmonary desease (COPD) patients admitted to the hospital for an excarebation. The IPV treatment is an additional treatment upon the standard treatment of the patients. The standard treatment consists out of existing drainage techniques to remove secretion out of the lungs by means of breathing control exercises. Patients are randomized into either the experimental group or the control group. The control group receives a standard physical therapy treatment without additional IPV treatment.

Enrollment: 20 estimated patients

Sex: All

Ages: 30+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients admitted in the hospital for a acute exacerbation
• Mild to severe COPD

Exclusion criteria

• Ischemic / ventricular aritmic
• Tracheotomise
• Pneumothorax
• Facial deformity
• Recent nose, mouth or ear operations
• Recent gastric operations.
• Intubated
• Epilepsy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Triple Blind

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20 participants in 2 patient groups

Intrapulmonary percussive ventilation

Experimental group

Description:

IPV is applied for 1 week (once a day) during the physical therapy treatment of the patient

Treatment:

Device: intrapulmonary percussive ventilation

standard airwy claerance regime

Active Comparator group

Description:

The standard treatment consists out of existing drainage techniques to remove secretion out of the lungs by means of breathing control exercises

Treatment:

Other: standard treatment