Effects of IV Administration of Ketamine on the Analgesia Nociception Index (ANI) Measured With the PhysioDoloris

University of Washington

Status: Completed

Conditions: Monitoring, Intraoperative

Study type: Observational

Funder types: Other

Identifiers

NCT01717521

42398

Details and patient eligibility

About

This study evaluates effects of the analgesic ketamine on ANI measurements (Anti Nociceptive Index)

Full description

Researchers at the University of Washington are doing this study to find out if a commonly used anesthetic affects patients Analgesia Nociception Index (level of pain relief) during abdominal hysterectomy under general anesthesia.

The investigators will administer routine anesthesia care including Ketamine, a commonly used anesthetic, during the patients surgery. During the patients surgery, the investigators will monitor the patients level of pain relief using the PhysioDoloris monitor, which monitors the routinely used EKG monitor. Though not yet FDA approved, the PhysioDoloris is completely non-invasive and collects data from the EKG monitor.

Enrollment: 20 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA status I, II, or III
• 18 years or older
• Receiving GA with uncomplicated routine intubation
• Ability to provide informed consent
• English-speaking

Exclusion criteria

• Presence of coronary artery disease, cardiac arrhythmias, or ketamine allergy
• Patient refusal
• History of substance abuse
• Patients taking psychotropic and/or opiate drugs
• Having a history of psychiatric diseases or psychological problems