Effects of IV Chloride Content on Outcomes

Baxter

Status: Completed

Conditions: SIRS; Plasmalyte; Balanced Fluids

Study type: Observational

Funder types: Industry

Identifiers

NCT02083198

Bax-BSP-HiLoCl

Details and patient eligibility

About

This observational study evaluates the impact of high and low chloride containing IV fluids on administrative and clinical outcomes. The study uses a large electronic health dataset and examines patients receiving fluid replacement and resuscitation. The hypothesis is that high chloride solutions are associated with adverse outcomes as measured by administrative data and by clinical parameters.

Enrollment: 1,558 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults meeting SIRS criteria receiving at least 500 mL of fluid replacement on day of SIRS.

Exclusion criteria

• Receipt of starches or other colloids

Trial design

1,558 participants in 2 patient groups

High Chloride

Description:

Patients receiving .9% sodium choride for resuscitation

Low chloride

Description:

Patients receiving Plasmalyte for resuscitation