Effects of Joint Effusion on Quadriceps Muscle

The Catholic University of Korea

Status: Completed

Conditions: Knee Osteoarthritis

Treatments: Other: sham injection; Other: normal saline injection

Study type: Interventional

Funder types: Other

Identifiers

NCT01314820

KC09OISI0161

Details and patient eligibility

About

The present study investigated whether the presence of fluid in the joint affected peak torque and the root mean square (RMS) values of surface electromyography (EMG) in patients symptomatic for osteoarthritis (OA).

Full description

Several studies have shown that knee effusion influenced quadriceps muscle activity and induced quadriceps arthrogenic muscle inhibition in normal volunteers. However, the effect of joint effusion on the quadriceps of patients with OA is controversial,and few patients with OA have been included in studies of joint effusion.

Enrollment: 40 patients

Sex: Female

Ages: 50 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 50 years old or older with knee osteoarthritis
• knee pain without joint effusion confirmed by ultrasonography

Exclusion criteria

• the presence of knee joint effusion determined using US
• a history of knee injury or surgery
• a history of knee injection within 3 months
• a history of inflammatory arthritis
• taking anticoagulants
• balance or gait disturbance
• diabetes mellitus

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

normal saline injection

Active Comparator group

Description:

20 cc normal saline injection into the knee joint

Treatment:

Other: normal saline injection

sham injection

Sham Comparator group

Description:

knee injection without saline

Treatment:

Other: sham injection