Effects of Light on Melatonin and Contractions in Pregnant Women

Mass General Brigham

Status: Completed

Conditions: Pregnancy

Treatments: Device: Lighting2; Device: Lighting1

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT01863446

1R21HD086392-01 (U.S. NIH Grant/Contract)

2012P002568

Details and patient eligibility

About

Specific Aim: Test the hypothesis that ocular light exposure will suppress melatonin secretion and reduce uterine contractions in women at late term pregnancies.

Secondary aim. Test the hypothesis that ocular light exposure will reduce self-reported uterine contractions in women at late term pregnancies.

Enrollment: 51 patients

Sex: Female

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• pregnant at 35-40 weeks
• first pregnancy

Exclusion criteria

• pregnancy-related complications
• twin or higher pregnancy
• using medication that affects the sympathetic nervous system

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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51 participants in 4 patient groups

Lighting1

Experimental group

Description:

Ocular light exposure of a red wavelength light for one night

Treatment:

Device: Lighting1

Lighting2

Experimental group

Description:

Ocular light exposure of a blue-green wavelength light for one night

Treatment:

Device: Lighting2

Lighting3

Experimental group

Description:

Ocular light exposure to a red wavelength light on night 1 and to a red wavelength light on night 2

Treatment:

Device: Lighting1

Lighting4

Experimental group

Description:

Ocular light exposure to a red wavelength light on night 1 and to a blue-green wavelength light on night 2

Treatment:

Device: Lighting1

Device: Lighting2