Effects of Low Intensity Blood Flow Restriction on Clinical Outcomes in Women With Knee Osteoarthritis (BFR)

University of Lahore

Status: Completed

Conditions: Osteoarthritis, Knee

Treatments: Other: Routine Physical Therapy; Other: BFRT

Study type: Interventional

Funder types: Other

Identifiers

NCT04865692

719-II

Details and patient eligibility

About

Objective is to compare the effects of routine physical therapy with and without low intensity blood flow restriction on pain and quadriceps muscle strength in women with knee osteoarthritis.

A single blinded randomized controlled trial conducted at Department of Physiotherapy, University of Lahore Teaching Hospital, Defense Road, Lahore.

Total 60 participants were randomly assigned in to two groups, with 30 in each group The intervention group received routine physiotherapy program combined with Low Intensity Blood Flow Restriction Technique (LI-BFR. While control group were treated with only routine physiotherapy.

Dynamometer was used to assess the knee extensor strength while Knee injury and osteoarthritis outcome score was used to record any exacerbation in pain and effects of BFR on activities of daily living. Training load determined 20% of 1RM. Data analysis had done on SPSS version 23.

Full description

nonparametric test Friedman test was for comparison within the groups and Mann Whitney U test was used for comparison between groups.

Randomization had done through the sealed envelope method. After allocation subjects had received their treatment protocals.

Enrollment: 60 patients

Sex: Female

Ages: 45 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Diagnosed patients of grade II knee osteoarthritis
• Patient's age 45-65

Exclusion criteria

• Bilateral knee replacement
• Lower limb surgery in the last six months
• Diagnosis of inflammatory joint or muscle disease
• Chest pain during exercise or at rest; or need for supplemental oxygen
• Pregnancy
• Any systemic disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 2 patient groups

Interventional group

Experimental group

Description:

The interventional group received resisted knee extension 20% of 1RM with blood flow restriction along with routine physical therapy.

Treatment:

Other: Routine Physical Therapy

Other: BFRT

Control Group

Other group

Description:

The Control group received routine physical therapy alone including knee isometrics and resisted knee extension

Treatment:

Other: Routine Physical Therapy