Effects of Low-Intensity Blood Flow Restriction Training in Normoxia and Hypoxia Conditions

The Jerzy Kukuczka Academy of Physical Education in Katowice

Status: Active, not recruiting

Conditions: Hypoxia, Altitude; Resistance Training; Blood Flow Restriction

Treatments: Other: high-intensity resistance training; Other: low-intensity resistance training; Other: low-intensity resistance training combined with blood flow restriction in hypoxia condition; Other: low-intensity resistance training combined with blood flow restriction; Other: low-intensity resistance training in hypoxia condition

Study type: Interventional

Funder types: Other

Identifiers

NCT06171841

SKN/SP/569582/2023

Details and patient eligibility

About

One approach to significantly reducing resistance training intensity while maintaining effectiveness in muscle mass and strength development involves conducting training sessions under hypoxic conditions. This is likely due to heightened physiological responses. While sports science research indicates a substantial impact of hypoxic conditions on immediate increases in metabolic stress and augmented hormonal responses, recent findings suggest that the role of their influence on skeletal muscle adaptations post-resistance training under hypoxic conditions remains unknown. Additionally, there is a lack of reports on whether the type of hypoxia applied via blood flow restriction or chamber differentiates the increase in secretion of these catecholamines in both immediate and long-term aspects.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Regularly physically active (at least 30 mins of structured exercise 3 times per week),
• Sea-level natives,
• Experienced in resistance training (at least one year of experience in regular resistance exercise)

Exclusion criteria

• presence of any medical risk factors to exercise and/or exposure to altitude
• presence of any medical condition that would make the protocol unreasonably hazardous for the participant
• smokers

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

60 participants in 5 patient groups

Low-Intensity Normoxia

Active Comparator group

Description:

Participants will be breathing room air, and perform low-intensity lower-body resistance exercise.

Treatment:

Other: low-intensity resistance training

High-Intensity Normoxia

Active Comparator group

Description:

Participants will be breathing room air, and perform high-intensity lower-body resistance exercise.

Treatment:

Other: high-intensity resistance training

Low-Intensity Normoxia with Blood Flow Restriction

Experimental group

Description:

Participants will be breathing room air, and perform low-intensity lower-body resistance exercise combined with blood flow restriction.

Treatment:

Other: low-intensity resistance training combined with blood flow restriction

Low-Intensity Hypoxia

Experimental group

Description:

Participants will be breathing a 13% oxygen gas mixture, and perform low-intensity lower-body resistance exercise.

Treatment:

Other: low-intensity resistance training in hypoxia condition

Low-Intensity Hypoxia with Blood Flow Restriction

Experimental group

Description:

Participants will be breathing a 13% oxygen gas mixture, and perform low-intensity lower-body resistance exercise combined with blood flow restriction.

Treatment:

Other: low-intensity resistance training combined with blood flow restriction in hypoxia condition