Effects of Low-level Laser Therapy on Global Gene Expression of Young Males Submitted to Physical Strength Training

U

Universidade Federal de Sao Carlos

Status

Completed

Conditions

Healthy

Treatments

Device: Low-level laser therapy and training
Other: Training

Study type

Interventional

Funder types

Other

Identifiers

NCT01784432
CAAE: 0150.0.135.000-10

Details and patient eligibility

About

Muscle performance is largely influenced by modulations in gene expressions of muscle tissue. In this context, low-level laser therapy has been used to improve muscle performance in experimental models and human researches. Thereby, the investigators examined modulations on global gene expression of muscle tissue influenced by exercise associated to low-level laser therapy.

Full description

This study assessed muscle performance in isokinetic dynamometry and leg press device; global gene expression of muscle tissue by microarray analysis

Enrollment

30 patients

Sex

Male

Ages

18 to 28 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • healthy males aged between 18 and 28 years;
  • body mass index (BMI) equal to or less than 26 kg/m2;
  • moderated pattern of physical activity

Exclusion criteria

  • previous injury to the femoral quadriceps or hamstring muscles (within 6 months prior to study),
  • osseous or articular disorder in the lower limbs,
  • cardiovascular system disorders,
  • systemic disease, and
  • taking prescription medicines or using dietary supplements such as muscle mass builders

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Factorial Assignment

Masking

None (Open label)

30 participants in 2 patient groups

Low-level laser therapy and training
Active Comparator group
Description:
Effects of low-level laser therapy on muscle performance during physical strength training and gene expression of muscle tissue.
Treatment:
Device: Low-level laser therapy and training
Training without low-level laser therapy
Active Comparator group
Description:
Effects of physical strength training without low-level laser therapy on muscle performance and gene expression of muscle tissue
Treatment:
Other: Training

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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