Effects of Low-level Laser Therapy on Global Gene Expression of Young Males Submitted to Physical Strength Training

Universidade Federal de Sao Carlos

Status: Completed

Conditions: Healthy

Treatments: Device: Low-level laser therapy and training; Other: Training

Study type: Interventional

Funder types: Other

Identifiers

NCT01784432

CAAE: 0150.0.135.000-10

Details and patient eligibility

About

Muscle performance is largely influenced by modulations in gene expressions of muscle tissue. In this context, low-level laser therapy has been used to improve muscle performance in experimental models and human researches. Thereby, the investigators examined modulations on global gene expression of muscle tissue influenced by exercise associated to low-level laser therapy.

Full description

This study assessed muscle performance in isokinetic dynamometry and leg press device; global gene expression of muscle tissue by microarray analysis

Enrollment: 30 patients

Sex: Male

Ages: 18 to 28 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy males aged between 18 and 28 years;
• body mass index (BMI) equal to or less than 26 kg/m2;
• moderated pattern of physical activity

Exclusion criteria

• previous injury to the femoral quadriceps or hamstring muscles (within 6 months prior to study),
• osseous or articular disorder in the lower limbs,
• cardiovascular system disorders,
• systemic disease, and
• taking prescription medicines or using dietary supplements such as muscle mass builders

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: None (Open label)

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30 participants in 2 patient groups

Low-level laser therapy and training

Active Comparator group

Description:

Effects of low-level laser therapy on muscle performance during physical strength training and gene expression of muscle tissue.

Treatment:

Device: Low-level laser therapy and training

Training without low-level laser therapy

Active Comparator group

Description:

Effects of physical strength training without low-level laser therapy on muscle performance and gene expression of muscle tissue

Treatment:

Other: Training