Effects of Low-volume Aerobic Interval Training in Overweight Individuals at Increased Cardiometabolic Risk (BELITA)

University of Erlangen-Nürnberg Medical School

Status: Completed

Conditions: Overweight and Obesity; Metabolic Syndrome

Treatments: Other: MIIT-LT; Other: HIIT; Other: Control; Other: MIIT-HR

Study type: Interventional

Funder types: Other

Identifiers

NCT03306069

BELITA-Study

Details and patient eligibility

About

The main purpose of this study is to compare the impact of aerobic interval training intensity on exercise adherence and changes in cardiorespiratory fitness, cardiometabolic risk profile, body composition, inflammatory markers and subjective health outcomes after a 12-week intervention trial in overweight individuals at increased cardiometabolic risk.

Enrollment: 154 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Body Mass Index >/=30
• presence of at least 2 cardiometabolic risk factors

Exclusion criteria

• Healthy persons or patients under age
• Overweight persons without any additional cardiometabolic risk factors
• Pregnancy, Lactation
• Psychological disorders, epilepsy, sever neurological disorders
• Participation in other exercise- or nutrition studies within the last 6 months
• acute cardiovascular disease
• malignant disease
• Electronic implants (defibrillator, pacemaker)
• Persons in mental hospitals by order of authorities or jurisdiction

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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154 participants in 4 patient groups

Control

Experimental group

Description:

Nutritional therapy / no exercise

Treatment:

Other: Control

HIIT

Experimental group

Description:

High-intensity interval training (HIIT) at 90% heart rate maximum (HRmax) combined with Nutritional therapy

Treatment:

Other: HIIT

MIIT-HR

Experimental group

Description:

Heart rate based moderate-intensity interval training (MIIT-HR) at 70% heart rate maximum (HRmax) combined with Nutritional therapy

Treatment:

Other: MIIT-HR

MIIT-LT

Experimental group

Description:

Lactate threshold based moderate-intensity interval training (MIIT-LT) at 105% of lactate threshold (corresponding \~70-75% HRmax) combined with Nutritional therapy

Treatment:

Other: MIIT-LT