Effects of Marihuana Use on Optic Nerve Parameters and Ocular Blood Flow

Israel Healthcare Foundation

Status: Unknown

Conditions: Intra Ocular Pressure

Study type: Observational

Funder types: Other

Identifiers

NCT02080676

CMC-14-0001-CTIL

Details and patient eligibility

About

Purpose of study: to check the effect of medical cannabis given for approved medical indications on ocular parameters including intra ocular pressure, optic nerve fibers thickness and choroidal thickness.

Full description

Purpose of study: to check the effect of medical cannabis given for approved medical indications on ocular parameters including intra ocular pressure, Retinal Nerve Fiber Layer (RNFL) thickness, optic nerve fibers thickness and choroidal thickness.

Adult patients with no ocular pathology that are being treated in the neurology or pain clinics with medical cannabis for different indications, were examined in the eye clinic.

First examination took place after the patient was not smoking for 5 hours. Three more examinations took place 1 hour 3 hours and 5 hours after smoking cannabis.

The following parameters were checked: blood pressure, pulse, visual acuity, intra ocular pressure, corneal thickness, axial length, slit lamp examination of anterior segment, fundoscopy and Optical Coherence Tomography (OCT) of the retina, and optic nerve.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age over 18
• Treated with medical cannabis for approved medical indications

Exclusion criteria

• Known ocular pathology
• Topical or systemic treatment for intra ocular pressure
• Previous topical, intra ocular or systemic steroid treatment