Effects of Maternal Obesity on Offspring Brain Development

Arkansas Children's Hospital Research Institute

Status: Active, not recruiting

Conditions: Healthy

Study type: Observational

Funder types: Other

Identifiers

NCT03499587

206551

Details and patient eligibility

About

The goal of this study is to see if there are negative effects of maternal obesity during pregnancy on offspring's brain development.

Full description

This study will recruit pregnant women who are either obese or normal weight and otherwise healthy. We will measure their body composition, food intake and other characteristics during pregnancy. When their babies are born, we will evaluate the brain development of their babies using magnetic resonance imaging and electroencephalography at age two weeks. We will then compare the findings and see if their are differences.

Enrollment: 13 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI 18.5-25 or >30 with early OB visit medical records accessible
• singleton pregnancy
• about 36wks of pregnancy
• at least 18 years of age

Exclusion criteria

• hypertension, diabetes, or other preexisting medical conditions
• medications known to influence fetal growth
• recreational drugs, nicotine or tobacco use of alcohol use while pregnant
• pregnancy conception with assisted fertility treatment
• medical complications developed during pregnancy

Trial design

13 participants in 2 patient groups

Obese pregnant women

Description:

BMI \>30 with early OB visit medical records accessible

Normal weight pregnant women

Description:

BMI 18.5-25 with early OB visit medical records accessible.