Effects of Mega-dose Vitamin D Pulse and Maintenance Therapy on Seizure Frequency, Fatigue, and Quality of Life: a Prospective Study

Chin-Wei Huang

Status: Not yet enrolling

Conditions: Epilepsy

Treatments: Other: Vitamin D; Other: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT06736002

B-BR-113-028

Details and patient eligibility

About

We inform consent overall process of this trial study through face-to-face use of the IRB, clarify patient questions, and allow subjects to fully understand the trial study.

Enrollment: 200 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Aged 20 or above (inclusive)
• Diagnosed patients (refractory epilepsy refers to those who have used more than two drugs, and each drug has reached the When epileptic seizures cannot be well controlled at standard reasonable treatment doses, it is called refractory epilepsy)
• There is no imaging evidence of persistence or expansion of brain damage in the past three years
• Subjects or family members (caregivers) can comply with the trial plan and take vitamin D patients

Exclusion criteria

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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200 participants in 2 patient groups, including a placebo group

Vitamin D

Experimental group

Treatment:

Other: Placebo

Other: Vitamin D

Placebo

Placebo Comparator group

Treatment:

Other: Placebo

Other: Vitamin D