Effects of Multidisciplinary Interventions in Elderly Asthma Patients With Risk of Acute Exacerbation

Sang-Heon Cho

Status: Unknown

Conditions: Asthma; Aged

Treatments: Behavioral: Inhaler technique training; Dietary Supplement: Magnesium; Behavioral: hot-lines for acute exacerbation of asthma; Behavioral: Education for asthma action plan

Study type: Interventional

Funder types: Other

Identifiers

NCT01843439

H-1205-083-410

Details and patient eligibility

About

We want to examine the effect of multidisciplinary interventions in asthma patients who had experienced acute exacerbation of asthma.

In our previous observational studies, elderly asthma patients had a some distinct features such as impairment of cognitive function, deficiency of micronutrient and absence of caregiver compared with young adult asthmatics.

We wanted to evaluate whether the long-term course of asthma could be modified by intervening deficienies which were found in elderly patiensts.

So, we designed a interventional study to correct above risk factors in elderly asthma patients, which could be aggravating their asthma. Followings are our specific multidiciplinary items that we want to correct.

1. popularize and educate the asthma action plan
2. run a emergency call system for acute exacerbation
3. educate the proper techniques using inhalers
4. correct the deficiency of magnesium (magnesium 500 mg per day)

After 1 years, we will measure the numbers of acute exacerbations, lung function including FEV1 and FEV1/FVC, health-related quality of life and level of serum magnesium in study patients.

Enrollment: 360 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• elderly asthma patients who had experienced acute exacerbation of asthma

  1)aggravations of any of major criteria

• dyspnea

• cough

• wheezing

• increase or purulent changes of sputum

• nocturnal symptoms

  2)aggravation of more than one of following criteria

• a reduction of forced expiratory volume at one second or peak expiratory flow rate more than 20% compared than one's best score

• unscheduled clinic or emergency department visit or admission

• step-up of dose of asthma medications or any intake of systemic steroids

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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360 participants in 1 patient group

Intervention

Experimental group

Description:

We designed a intervention study to correct additional risk factors in elderly asthma patients. We offer following specific interventions simultaneously to intervention arm and will measure the effects of interventions after 1 years. 1. popularize and educate the asthma action plan 2. run a emergency call system for acute exacerbation 3. educate the proper techniques using inhalers 4. correct the deficiency of magnesium (magnesium 500mg per day)

Treatment:

Behavioral: Education for asthma action plan

Behavioral: hot-lines for acute exacerbation of asthma

Dietary Supplement: Magnesium

Behavioral: Inhaler technique training