Effects of Muscle Energy Technique in Knee Osteoarthritis Patients

Riphah International University

Status: Completed

Conditions: Knee Osteoarthritis

Treatments: Other: MUSCLE ENERGY TECHNIQUE; Other: CONVENTIONAL PHYSICAL THERAPY

Study type: Interventional

Funder types: Other

Identifiers

NCT05349565

REC/01255 Fanila Ashraf

Details and patient eligibility

About

To determine the effectiveness of muscle energy technique along conventional physical therapy after mesenchymal stem cell transplantation in knee Osteoarthritis patients regarding Pain, range of motion, functional disability and quality of life.

Full description

Mesenchymal stem cells (MSCs) replacement is a regenerative therapeutic procedures for the early treatment of cartilaginous defects in knee osteoarthritis. MSCs may improve symptoms and function in osteoarthritic joints but also decrease inflammation and induce cartilage healing by differentiating into chondrocytes, osteoblasts and indicating appropriate extracellular matrix proteins (i.e. collagen I and II) through the secretion of cytokines, chemokines, and growth factors from MSCs.

Enrollment: 26 patients

Sex: All

Ages: 41 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Both male and female
• Age > 40 years
• Knee osteoarthritis patients undergone mesenchymal stem cell transplantation.

Exclusion criteria

• History of recent or past septic arthritis
• Patients with neurological deficit
• Uncontrolled diabetes
• Malignancy
• Vascular insufficiency

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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26 participants in 2 patient groups

CONVENTIONAL PHYSICAL THERAPY

Active Comparator group

Description:

TENS , Open chain knee flexion and extension, Calf stretch , Quad set

Treatment:

Other: CONVENTIONAL PHYSICAL THERAPY

MUSCLE ENERGY TECHNIQUE

Experimental group

Description:

MET ( isometric contraction with 6-10 sec )

Treatment:

Other: MUSCLE ENERGY TECHNIQUE