Effects of N-acetylcysteine on Pulmonary Function in High-risk Patients Undergoing Off-pump Coronary Bypass Surgery

Yonsei University

Status and phase: Completed; Phase 4

Conditions: Coronary Artery Occlusion

Treatments: Drug: N-acetylcysteine, saline

Study type: Interventional

Funder types: Other

Identifiers

NCT01021163

4-2007-0236

Details and patient eligibility

About

The purpose of this study is to study the effects of N-acetylcysteine on pulmonary function in high-risk patients undergoing off-pump coronary bypass surgery.

Enrollment: 48 patients

Sex: All

Ages: 20+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adult patients with Euroscore ≥ 5

Exclusion criteria

• Patients in need of emergency surgery,acute renal failure patients, kidney transplanted patients, patients injected with NAC 5days before planned surgery

Trial design

48 participants in 1 patient group, including a placebo group

N-acetylcysteine , saline

Placebo Comparator group

Treatment:

Drug: N-acetylcysteine, saline