Effects of Naproxen on Physical Performance

University of Oklahoma (OU)

Status and phase: Terminated; Phase 4

Conditions: Healthy

Treatments: Drug: Naproxen

Study type: Interventional

Funder types: Other

Identifiers

NCT00410995

11186 (Registry Identifier)

Details and patient eligibility

About

The purpose of this study is to determine the effect of daily use of Naproxen (a commonly used over-the-counter NSAID) on the physical performance of athletes, as measured by maximum oxygen consumption.

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Age equal to or greater than18 years of age
2. No history of allergy or adverse reaction to any NSAID
3. No use of any NSAID in past 2 weeks
4. No history of peptic ulcer disease (PUD), gastroesophageal disease (GERD), or gastritis
5. No major medical history including but not limited to diabetes, hypertension, asthma, kidney disease and coronary artery disease
6. Currently not taking any medication including oral contraceptives

Exclusion criteria

1. Age < 18 years of age
2. History of allergy or adverse reaction to any NSAID
3. Use of any NSAID in past 2 weeks
4. History of a bleeding disorder
5. History of PUD, GERD, or gastritis
6. Pregnant
7. A medical history of diabetes, hypertension, asthma, kidney disease or coronary artery disease
8. Taking any medication including oral contraceptives

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)