Effects of Negative Pressure Ventilation on Right Ventricular Function in Cardiological Patients

Karlsburg Hospital

Status: Not yet enrolling

Conditions: Right Ventricular Failure; Right Ventricular Dysfunction; Negative Pressure Ventilation

Treatments: Device: Negative Pressure Ventilation

Study type: Observational

Funder types: Other

Identifiers

NCT06572072

KAIKB-2024_1

Details and patient eligibility

About

Patients receives induction of general anesthesia for interventional tricuspidal clipping and standard monitoring for this procedure including arterial and central venous line and transesophageal ultrasound. A cuirass for extrathoracal negative pressure ventilation is placed onto the chest but not switched on. During usual positive pressure ventilation a ventilatory, a hemodynamic and a 3D full volume ultrasounddataset of the right and left ventricle is recorded and severity of tricuspidal regurgitation examined. Afterwards negative pressure ventilation is started and positive pressure ventilation reduced as far as possible without reduction of tidal volumes. The same dataset of ventilation, hemodynamics and ultrasound is collected again during negative pressure ventilation. Afterwards the cuirass gets removed, study finished and everything proceeds as during standard procedure.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients planned for tricuspidal clipping

Exclusion criteria

• ventilatory of hemodynamic instability
• fitting of cuirass not possible
• unavailability of examiner