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Effects of OCTA-guided PDT in Acute CSC

P

Peking University

Status

Completed

Conditions

Tomography, Optical Coherence
Central Serous Chorioretinopathy

Treatments

Procedure: ICGA-guided Photodynamic therapy
Procedure: OCTA-guided Photodynamic therapy

Study type

Interventional

Funder types

Other

Identifiers

NCT03497000
Peking UPH

Details and patient eligibility

About

OCTA-guided PDT is as safe and effective as ICGA-guided PDT in the treatment of acute central serous chorioretinopathy. Or OCTA-guided PDT is more effective than ICGA-guided PDT in the treatment of acute central serous chorioretinopathy, safe as well.

Enrollment

23 patients

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Idiopathic detachment of the neurosensory retina with a focal leak at the level of the RPE with FA
  • Presence of SRF and/or serous pigment epithelial detachment on OCT
  • Presence of abnormal dilated choroidal vasculature in ICGA

Exclusion criteria

  • Patients with other ocular conditions commonly associated with SRF, such as choroidal neovascularization, polypoidal choroidal vasculopathy (PCV), diabetic retinopathy, retinal vascular occlusion, Coat's disease
  • Any disease that may affect the quality of imaging (quality of OCTA images < 6), such as cataract, high myopia or nystagmus
  • History of ocular surgeries including retinal laser
  • Pregnancy
  • Any uncontrolled systemic disease
  • Any condition rendering patients intolerable to image acquisition

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Triple Blind

23 participants in 2 patient groups

OCTA group
Experimental group
Description:
Patients in this group underwent OCTA-guided half-dose photodynamic therapy.
Treatment:
Procedure: OCTA-guided Photodynamic therapy
ICGA group
Active Comparator group
Description:
Patients in this group underwent normal ICGA-guided half dose photodynamic therapy.
Treatment:
Procedure: ICGA-guided Photodynamic therapy

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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