Effects of Omega-3 and Whey Protein Supplementation on Lean Mass in Older Adults (W-3 and Whey)

Federal University of Uberlandia

Status

Enrolling

Conditions

Sarcopenia

Treatments

Dietary Supplement: Placebo Group

Dietary Supplement: Whey Protein + Placebo

Dietary Supplement: Omega 3 + Whey Protein

Dietary Supplement: Omega 3 + Placebo

Study type

Interventional

Funder types

Other

Identifiers

NCT05862779

5.728.049

Details and patient eligibility

About

To evaluate the effect of omega-3 supplementation combined with whey protein intake on lean mass and strength gains in older adults performing resistance exercise. Participants will be randomized into the 4 groups. The placebo group will receive 4 g per day of corn oil and 40 g per day of maltodextrin. The omega 3 + placebo group will receive 4 g per day of fish oil and 40 g per day of maltodextrin. The whey protein + placebo group will receive 40g per day of whey and 4g per day of corn oil. The omega 3 + whey group will receive 4g per day of fish oil and 40g per day of protein. All will perform the same exercise protocol for 12 weeks

Enrollment

80 estimated patients

Sex

Female

Ages

60 to 85 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Postmenopausal women (at least 1 year of menstrual interruption, self-reported);
To be able to practice strength exercises;
To be able to carry out supplementation;
Do not present physical, orthopedic or cardiovascular complications that prevent the performance of physical exercises;
No history of stroke or acute myocardial infarction;
Not being a smoker and/or alcoholic;
Do not perform hormone replacement therapy;
Do not use anti-inflammatory drugs;
To have normal kidney function;
To submit a medical certificate of health that proves that the individual is able to perform exercises.

Exclusion criteria

Do not provide the necessary information for the development of the study;
Individuals with diseases previously diagnosed and undergoing treatment, such as type II diabetes mellitus, cancer, rheumatoid arthritis, high blood pressure, dyslipidemia, cardiovascular, and kidney and/or liver diseases.

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Triple Blind

80 participants in 4 patient groups, including a placebo group

Placebo Group

Placebo Comparator group

Description:

Group supplemented with maltodextrin (40g/day) and corn oil (4g/day). All groups will undergo a training program with strength exercises for 12 weeks

Treatment:

Dietary Supplement: Placebo Group

Whey Protein + Placebo

Experimental group

Description:

Group supplemented with isolated whey protein (40g/day) and corn oil (4g/day). All groups will undergo a training program with strength exercises for 12 weeks.

Treatment:

Dietary Supplement: Whey Protein + Placebo

Omega 3 + Placebo

Experimental group

Description:

Group supplemented with omega-3 (4g/day) and maltodextrin (40g/day). All groups will undergo a training program with strength exercises for 12 weeks.

Treatment:

Dietary Supplement: Omega 3 + Placebo

Omega 3 + Whey Protein

Experimental group

Description:

Group supplemented with omega-3 (4g/day) and whey protein (40g/day). All groups will undergo a training program with strength exercises for 12 weeks.