Effects of Oral L-Arginine on Chronic Hypertension in Pregnancy

University of Modena and Reggio Emilia

Status and phase: Completed; Phase 3

Conditions: Hypertension in Pregnancy

Treatments: Drug: Placebo; Drug: L-Arginine

Study type: Interventional

Funder types: Other

Identifiers

NCT00571766

Oral L-Arginine

Details and patient eligibility

About

The purpose of this study is to evaluate the effects of oral L-Arginine in pregnant women with chronic hypertension.

Enrollment: 80 estimated patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Pregnant women between 18-20 week of gestation with chronic hypertension

Exclusion criteria

• Maternal or fetal disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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80 participants in 2 patient groups, including a placebo group

1

Experimental group

Description:

Oral L-Arginine 2 g twice a day for 14 weeks

Treatment:

Drug: L-Arginine

2

Placebo Comparator group

Description:

Placebo 2 g, twice a day for 14 weeks

Treatment:

Drug: Placebo