Effects of Orthognathic Surgery on Root Resorption and Soft Tissues

Gokhan Coban

Status: Completed

Conditions: Orthognathic Surgical Procedures; Orthodontics

Treatments: Procedure: Surgery Early; Procedure: Surgery First

Study type: Interventional

Funder types: Other

Identifiers

NCT06873451

2023-655

Details and patient eligibility

About

The aim of this study is to evaluate the three-dimensional tomographic and photographic evaluation of the provision of two different orthognathic surgeries on hard and soft tissues with informative Class III deformity due to maxillary retrognathia and mandibular prognathia.

Full description

Patients who will undergo non-extraction surgery will be randomized as 'Pre-Surgery' (SEC) and 'Early Surgery' (EC). Maxillary advancement and mandibular recession will be calculated and a total of 24 patients, 12 in each group, will be included in the study. Millimetric (length, dehiscence, fenestration) and volumetric measurements and soft tissue anthropometric points will be measured in three-dimensional recordings taken at the beginning of treatment (T0) and after debonding (T1). Cone beam computed tomography (CBCT) images will be transferred to NNT and 'Mimics 18.0' programs for measurements. Three-dimensional photographs will be evaluated in the 3dMDvultus program. Shapiro-Wilk test will be used for normality, 'two independent samples t-test' and 'Mann Whitney U test' will be used for intra-group and inter-group comparisons.

Enrollment: 24 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• They must be over 18 years of age,
• Skeletal Class III malocclusion and need double jaw orthognathic surgery,
• Minimum crowding (patients with crowding between 0-3 mm),
• Complete 3D records before surgery and at the end of treatment,
• No decay on their teeth,
• Good oral hygiene,
• Healthy periodontal tissues.

Exclusion criteria

• History of trauma,
• Congenital anomalies or craniofacial deformities
• Congenital tooth loss (excluding wisdom teeth)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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24 participants in 2 patient groups

Surgery First

Experimental group

Description:

Patients in this group started with surgical treatment directly without receiving orthodontic treatment and started orthodontic treatment after surgery.

Treatment:

Procedure: Surgery First

Surgery Early

Experimental group

Description:

Patients in this group were referred to orthognathic surgery after receiving orthodontic treatment for an average of 6-8 months, and their orthodontic treatments continued after surgery.

Treatment:

Procedure: Surgery Early