Effects of Oxybutynin Topical Gel on Gastric Emptying

Watson Pharmaceuticals

Status and phase: Completed; Phase 1

Conditions: Healthy

Treatments: Drug: Oxybutynin Chloride Gel; Drug: Placebo Gel

Study type: Interventional

Funder types: Industry

Identifiers

NCT00926926

OTG0901

Details and patient eligibility

About

This study explores the effect of oxybutynin topical gel on gastric emptying

Enrollment: 23 patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adult, healthy, post-menopausal females

Exclusion criteria

• Patients for whom OTG or acetaminophen is contraindicated.
• Abnormality of the GI tract.
• Taking drugs that affect gastric motility.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Quadruple Blind

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23 participants in 2 patient groups, including a placebo group

Active OTG

Experimental group

Treatment:

Drug: Oxybutynin Chloride Gel

Placebo

Placebo Comparator group

Treatment:

Drug: Placebo Gel